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“Objective: To provide an update of the advantages of new-generation molecular diagnostics to study the diversity of intestinal microflora and to evaluate its alteration in human diseases. Methods: We review recent advances in understanding the complex ecosystem of gut microbiota based on a dynamic and mutual interaction with the host. Results: In vaginal delivery, the contact with the mother’s vaginal and intestinal flora is an important source of Lactobacillus, Prevotella and other Bifidobacterium. On the opposite, in cesarean delivery,
direct contact of the mouth of the newborn with vaginal and intestinal microbiota is replaced by exogenous non-maternally derived bacteria colonizing the infants’ intestine producing a less diverse flora. The original microbiome settings evolve during the growth converging to three main clusters defined “enterotypes” selleck chemicals in the adult age. Conclusions: The key role in human health could depend on the balance between beneficial and harmful microbial species populating the gut, therefore the intestinal microflora can been considered MAPK inhibitor as a potential biomarker and/or therapeutic target in intestinal and extra-intestinal diseases.”
“We examined the effect
of magnesium (Mg) on the charophytes calcite (CaCO(3)) encrustation and assessed whether charophytes, growing on non-calcareous sediments in the Myall P505-15 Angiogenesis inhibitor Lake, a poorly flushed shallow coastal lake with salinity of 2-3 PSU, could function as an effective nutrient sink for phosphorus (P) in a similar manner to charophytes growing on calcareous sediments of the freshwater calcium (Ca)-rich hardwater, i.e., through the formation of Ca-bound P. Our results showed that high Mg in the Myall Lake water reduced the calcification in charophytes. Likewise, the addition of Mg into the tap water also produced the same effect. The inhibition of the calcite formation decreased significantly the percentage of Ca-bound P formation in the
charophyte biomass as well as in the sediment. However, the inability of charophytes in Myall Lake to precipitate calcite does not reduce the plant beds’ capability to act as a P nutrient sink. Instead of Ca- bound P, a large percentage of less bioavailable non-reactive organically bound P (NaOH-P: 40-65%) fraction in the biomass, together with the plant’s slow decomposition rate, will lead to burial of dead organic matter and an incomplete mineralization process. In particular, detritus of the charophyte plants’ thalli is relatively more resistant to mineralization. This mechanism was supported by the result of sedimentary P fractionation in which the refractory P and non-reactive organic P fractions accounted for at least 80% of the total P.”
“Improved management of agricultural soils has potential for sequestering carbon (C) and reducing the accumulation of atmospheric carbon dioxide.